Question: Pharmaceutical Co-crystals for improving drug performance
In the current course work explain
What pharmaceutical co-crystals are including the following aspects:
- advantages of co-crystals compared to the bulk API
- how the selection of the drug-conformer pair is done
- discuss 3-4 main synthesis methods
- provide three case studies for the formation of co-crystals and discuss the properties of the synthesised compounds
- provide a brief discussion from a regulatory point of view